[Retroperitoneal Cellular Angiofibroma: A Rare Gynecological Entity]

Area of Science:

• Gynecologic Oncology
• Surgical Pathology
• Medical Oncology

Background:

• Cellular angiofibroma is a rare mesenchymal neoplasm first described in 1997.
• It typically presents in adults without gender predilection, commonly in the vulvovaginal region.
• While often superficial, deep or extra-pelvic presentations are infrequently reported.

Observation:

• A case is presented of a woman with a heterogeneous tumor in the right adnexal region.
• Surgical exploration revealed a retroperitoneal tumor.
• Histopathological analysis confirmed the diagnosis of cellular angiofibroma.

Findings:

• The excised retroperitoneal tumor was diagnosed as cellular angiofibroma.
• This finding expands the known anatomical distribution of this rare tumor.
• The histopathological features were consistent with established criteria for cellular angiofibroma.

Implications:

• This case underscores the importance of considering cellular angiofibroma in the differential diagnosis of retroperitoneal masses.
• It highlights the need for accurate histopathological evaluation for definitive diagnosis and appropriate management.
• Complete surgical excision remains the primary treatment, with a generally low recurrence rate for cellular angiofibroma.