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Dismantling cognitive-behaviour therapy for panic disorder: a systematic review and component network meta-analysis
Alessandro Pompoli1, Toshi A Furukawa2, Orestis Efthimiou3
1MD, Psychiatric Rehabilitation Clinic Villa San Pietro,Trento,Italy.
Psychological Medicine
|January 26, 2018
Summary
Cognitive-behaviour therapy (CBT) for panic disorder is more effective when it includes interoceptive exposure and face-to-face sessions. Excluding muscle relaxation and virtual-reality exposure enhances treatment outcomes for panic disorder.
Area of Science:
- Psychiatry
- Clinical Psychology
- Evidence-Based Medicine
Background:
- Cognitive-behaviour therapy (CBT) for panic disorder comprises various components.
- Understanding the efficacy of individual CBT components is crucial for optimizing treatment.
Purpose of the Study:
- To determine the comparative effectiveness of different components within CBT for panic disorder.
- To identify optimal combinations of CBT components for treating panic disorder.
Main Methods:
- Component network meta-analysis (NMA) of randomized controlled trials.
- Inclusion of 72 studies with 4064 participants comparing CBT interventions for panic disorder.
Main Results:
- Interoceptive exposure and face-to-face settings demonstrated superior efficacy and acceptability.
- Muscle relaxation and virtual-reality exposure were associated with lower efficacy.
- Breathing retraining and in vivo exposure showed improved acceptability with minor efficacy effects.
Conclusions:
- Effective CBT for panic disorder should incorporate face-to-face and interoceptive exposure.
- Excluding muscle relaxation and virtual-reality exposure is recommended for enhanced panic disorder treatment outcomes.
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