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Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
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Cicatricial alopecia.

Pier A Fanti1, Carlotta Baraldi2, Cosimo Misciali1

  • 1Unit of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia
|January 26, 2018
PubMed
Summary
This summary is machine-generated.

Cicatricial alopecias (CAs) involve irreversible hair follicle destruction, leading to scarring. These conditions are categorized into primary (PCA) and secondary (SCA) types, based on the initial cause of follicle damage.

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Cicatricial alopecias (CAs) are a group of disorders characterized by the destruction of hair follicles and their replacement by fibrotic tissue.
  • Clinically, CAs present with diverse inflammatory patterns culminating in the loss of hair follicles and follicular openings.
  • These conditions result in permanent alopecia, posing significant clinical challenges.

Purpose of the Study:

  • To elucidate the classification and underlying mechanisms of cicatricial alopecias.
  • To differentiate between primary and secondary forms of cicatricial alopecia based on etiological factors and histopathological findings.

Main Methods:

  • Review of clinical and histopathological features of cicatricial alopecia cases.
  • Classification of alopecias into primary cicatricial alopecia (PCA) and secondary cicatricial alopecia (SCA) based on disease origin.

Main Results:

  • CAs lead to the complete and irreversible destruction of hair follicles.
  • Primary cicatricial alopecias (PCAs) originate from inflammatory diseases directly targeting the hair follicle.
  • Secondary cicatricial alopecias (SCAs) result from conditions like inflammation, neoplasms, or trauma that secondarily damage the hair follicle.

Conclusions:

  • Cicatricial alopecias represent a spectrum of conditions with distinct pathological pathways.
  • Accurate classification into PCA and SCA is crucial for understanding disease pathogenesis and guiding treatment strategies.