Jove
Visualize
Contact Us

Related Concept Videos

Correlations02:20

Correlations

36.6K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
36.6K
Correlation and Causation01:27

Correlation and Causation

43.0K
Statistical tests can calculate whether there is a relationship, or correlation, between independent and dependent variables. An indirect relationship of the variables signifies a correlation, while a direct relationship shows causation. If it is determined that no connection exists between the variables, then the correlation is a coincidence.
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
43.0K
Correlation01:09

Correlation

15.2K
In statistics, two variables are said to be correlated if the values of one variable are associated with the other variable. Depending on the relationship between two variables, correlation can be of three types– positive correlation, negative correlation, and zero correlation.
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
15.2K
Correlation and Regression00:53

Correlation and Regression

3.5K
In statistics, correlation describes the degree of association between two variables. In the subfield of linear regression, correlation is mathematically expressed by the correlation coefficient, which describes the strength and direction of the relationship between two variables. The coefficient is symbolically represented by 'r' and ranges from -1 to +1. A positive value indicates a positive correlation where the two variables move in the same direction. A negative value suggests a...
3.5K
Coefficient of Correlation01:12

Coefficient of Correlation

8.7K
The correlation coefficient, r, developed by Karl Pearson in the early 1900s, is numerical and provides a measure of strength and direction of the linear association between the independent variable x and the dependent variable y.
If you suspect a linear relationship between x and y, then r can measure how strong the linear relationship is.
What the VALUE of r tells us:
The value of r is always between –1 and +1: –1 ≤ r ≤ 1.
The size of the correlation r indicates the...
8.7K
Correlation of Experimental Data01:23

Correlation of Experimental Data

492
Dimensional analysis simplifies complex physical problems and guides experimental investigations, but it does not provide complete solutions. It identifies the dimensionless groups that influence a phenomenon, but experimental data is needed to establish the specific relationships and validate theoretical predictions.
For example, a spherical particle moving through a viscous fluid experiences drag. Dimensional analysis shows that the drag force depends on the particle's diameter, velocity,...
492

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bullous Wells' Syndrome: Case Report and Systematic Review.

Journal of clinical medicine·2025
Same author

Concomitant cutaneous T-cell lymphoma and biclonal B-cell lymphoproliferative disorder.

Cytometry. Part B, Clinical cytometry·2024
Same author

Tattoo-Associated Skin Reaction in a Melanoma Patient Receiving B-RAF and MEK Inhibitors: A Case Report with an Emphasis on Etiopathogenic and Histological Features.

Journal of clinical medicine·2024
Same author

Enhanced Delivery of 5-Aminolevulinic Acid by Lecithin Invasomes in 3D Melanoma Cancer Model.

Molecular pharmaceutics·2023
Same author

Granulomatous Secondary Syphilis: A Case Report with a Brief Overview of the Diagnostic Role of Immunohistochemistry.

Pathogens (Basel, Switzerland)·2023
Same author

Congenital Cutis Verticis Gyrata in a Newborn with Turner Syndrome: A Rare Clinical Manifestation of This Chromosomal Disease with Trichoscopic Evaluation.

Diagnostics (Basel, Switzerland)·2023
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Feb 15, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

705

Cutaneous lupus erythematosus: clinico-pathologic correlation.

Raffaele Filotico1, Valentina Mastrandrea2

  • 1Unit of Dermatology, "A. Perrino" Hospital, Brindisi, Italy - raffaelefilotico@libero.it.

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia
|January 26, 2018
PubMed
Summary

Cutaneous lupus erythematosus (CLE) is a chronic skin disease with unknown causes, often triggered by genetics and environment. Early diagnosis and management, including photoprotection and specific therapies, are crucial for preventing disease progression and scarring.

More Related Videos

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

18.7K
Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

1.1K

Related Experiment Videos

Last Updated: Feb 15, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

705
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

18.7K
Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

1.1K

Area of Science:

  • Dermatology
  • Immunology
  • Autoimmune Diseases

Background:

  • Cutaneous lupus erythematosus (CLE) is a chronic autoimmune skin condition.
  • It affects approximately 73 out of 100,000 individuals.
  • CLE serves as a prototype for autoimmune diseases, influenced by genetic and environmental factors.

Purpose of the Study:

  • To classify the clinical variants of cutaneous lupus erythematosus.
  • To describe the histopathological features of CLE.
  • To outline the therapeutic strategies for managing CLE and preventing systemic lupus erythematosus (SLE) progression.

Main Methods:

  • Classification of CLE into acute (ACLE), subacute (SCLE), chronic (CCLE), and intermittent (ICLE) forms.
  • Histopathological analysis of skin lesions, including interface dermatitis, lymphocytic infiltrate, and PAS material deposits.
  • Review of therapeutic approaches, emphasizing photoprotection, topical treatments, and systemic medications like hydroxychloroquine.

Main Results:

  • CLE presents with specific histopathological findings like basal layer vacuolization and dermal infiltrate.
  • Non-specific skin lesions can indicate progression towards systemic lupus erythematosus (SLE), occurring in 12-18% of CLE cases.
  • Therapeutic interventions focus on preventing disease recurrence and scarring.

Conclusions:

  • CLE is a distinct skin disease with varied clinical and histopathological presentations.
  • Understanding CLE's relationship with SLE is critical for patient management.
  • Effective management involves photoprotection, topical therapies, and systemic treatments, with hydroxychloroquine as a primary choice.