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Risk factors for urinary tract infection in children with urinary urgency
Rhaiana Gondim1, Roberta Azevedo1, Ana Aparecida Nascimento Martinelli Braga1
1Centro Pediátrico de Distúrbios Urinários (CEDIMI), Salvador, BA, Brasil.
Insights
Female sex and infrequent voiding are significant predictors of febrile urinary tract infection (UTI) in children and adolescents with overactive bladder. These findings highlight key risk factors for febrile UTI in this population.
Area of Science:
- Pediatrics
- Urology
- Infectious Diseases
Background:
- Overactive bladder (OAB) is a common condition in children and adolescents.
- Febrile urinary tract infection (UTI) is a serious complication that requires prompt diagnosis and management.
- Identifying predictors of febrile UTI in pediatric OAB patients is crucial for risk stratification and prevention.
Purpose of the Study:
- To determine the independent variables that are strong predictors of febrile urinary tract infection (UTI) in children and adolescents diagnosed with overactive bladder.
- To identify risk factors associated with febrile UTI in a pediatric population with OAB.
Main Methods:
- Retrospective analysis of a database of patients diagnosed with overactive bladder over four years.
- Inclusion criteria: children and adolescents under 18 with OAB, excluding those with neurological or anatomical lower urinary tract alterations.
- Statistical analysis included univariate and multivariate assessments to identify predictors of febrile UTI.
Main Results:
- A total of 326 patients (214 girls, 112 boys) were evaluated, with a mean age of 7.7 years.
- The incidence of febrile UTI was 39.2% in the study cohort.
- Being female and infrequent voiding (≤3 voids/day) were identified as significant risk factors for febrile UTI.
Conclusions:
- Female sex and infrequent voiding are significant risk factors for febrile UTI in children and adolescents with overactive bladder.
- These findings can aid in identifying high-risk individuals for targeted interventions and improved patient outcomes.
- Further research may explore the underlying mechanisms linking these factors to febrile UTI in pediatric OAB.
Purpose:
To identify which independent variable would be strong predictor of febrile urinary tract infection (UTI) in children and adolescents with overactive bladder.
Materials And Methods:
A search was made of the institute's database for all patients diagnosed with overactive bladder over the preceding four years. Children and adolescents under 18 years of age with overactive bladder and no neurological or anatomical alterations of the lower urinary tract were included in the study. The independent variables were: sex, age, ethnicity (Brazilians of African descendence/others), the presence of urinary urgency, daytime incontinence, enuresis, frequent urination, infrequent voiding (≤3 voids/day), nocturia, holding maneuvers, straining to void, intermittent urinary flow, constipation and encopresis. An analysis was conducted to identify patients with febrile UTI and subsequently determine predictors of this condition. Univariate and multivariate analyses were performed.
Results:
Overall, 326 patients (214 girls/112 boys) were evaluated. The mean age of the patients was 7.7±3.19 years (± standard deviation). The incidence of febrile UTI was 39.2%. Being female and infrequent voiding were factors significantly associated with febrile UTI, both in the univariate and multivariate analyses.
Conclusions:
These results show that being female and infrequent voiding constituted significant risk factors for a diagnosis of febrile UTI in these children.
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