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Updated: Feb 15, 2026

Chemical Dimerization-Induced Protein Condensates on Telomeres
Published on: April 12, 2021
A new phenanthrene dimer from Dendrobium palpebrae
Napat Kyokong1, Chawanphat Muangnoi2,3, Wuttinont Thaweesest2,3
1a Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany , Chulalongkorn University , Bangkok 10330 , Thailand.
Abstract:
A new phenanthrene dimer, namely dendropalpebrone (1), was isolated from the whole plant of Dendrobium palpebre, along with nine known compounds (2-10). All of the isolates were evaluated for their hydroxyl radical scavenging effects using a deoxyribose assay. Dendroflorin (10) showed an appreciable activity, and therefore was selected for further studied in RAW264.7 cells. Compound 10 significantly decreased ROS in H2O2-stimulated RAW264.7 cells in a dose-dependent manner, and improved activity of SOD, GPx, and CAT enzymes.
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