Related Experiment Video
Updated: Feb 15, 2026

Assessment of Thermal Damage from Robot-Drilled Craniotomy for Cranial Window Surgery in Mice
Published on: November 11, 2022
Three-Dimensional Blood Vessel Model with Temperature-Indicating Function for Evaluation of Thermal Damage during
Takeshi Hayakawa1, Hisataka Maruyama2, Takafumi Watanabe3
1Room 310, Aerospace Mechanical Engineering Research Building 3F, Department of Micro-Nano Mechanical Science & Engineering, Nagoya University, Furo-cho, Chikusa-ku, Aichi-Pref., Nagoya-shi 464-8603, Japan. t-hayakawa@mech.nagoya-u.ac.jp.
Abstract:
Surgical simulators have recently attracted attention because they enable the evaluation of the surgical skills of medical doctors and the performance of medical devices. However, thermal damage to the human body during surgery is difficult to evaluate using conventional surgical simulators. In this study, we propose a functional surgical model with a temperature-indicating function for the evaluation of thermal damage during surgery. The simulator is made of a composite material of polydimethylsiloxane and a thermochromic dye, which produces an irreversible color change as the temperature increases. Using this material, we fabricated a three-dimensional blood vessel model using the lost-wax process. We succeeded in fabricating a renal vessel model for simulation of catheter ablation. Increases in the temperature of the materials can be measured by image analysis of their color change. The maximum measurement error of the temperature was approximately -1.6 °C/+2.4 °C within the range of 60 °C to 100 °C.
Related Concept Videos
Temperature and Thermal Equilibrium
The concept of temperature has evolved from the common concepts of hot and cold. The scientific definition of temperature explains more than just our sense of hot and cold. Temperature is operationally defined as the quantity measured with a thermometer. Furthermore, temperature is...
Anatomy of Blood Vessels
Arteries
Arteries circulate oxygenated blood from the heart, except the pulmonary artery, which transports deoxygenated blood to the lungs. Large arteries, such as the aorta,...
Structure of Blood Vessels
Development of Blood Vessels
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
Overview of Blood Vessels
Arteries and Arterioles: Arteries are muscular and elastic vessels that primarily carry oxygenated blood from the heart to body tissues, except for the pulmonary artery, which carries deoxygenated blood. They have thick walls to withstand high pressure and contain a layer of muscle tissue, allowing them to expand or contract as...
Characteristics and Functions of Blood
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...

