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[Lower-extremity artery disease (LEAD)]

Alessandra Bura-Rivière1, Romain Martin1

  • 1Hôpital universitaire de Rangueil, service de médecine vasculaire, 1, avenue Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France.

Presse Medicale (Paris, France : 1983)
|January 27, 2018
PubMed

Insights

Women face similar risks of lower-extremity artery disease (LEAD) as men, but their symptoms are often missed, leading to late diagnosis. Consequently, women experience higher complication rates after revascularization procedures.

Area of Science:

  • Vascular Surgery
  • Peripheral Artery Disease Research
  • Gender Health Disparities

Background:

  • Lower-extremity artery disease (LEAD) affects both genders, but clinical presentation and outcomes may differ.
  • Underdiagnosis and delayed treatment in women can lead to advanced disease stages.
  • Existing research often overlooks gender-specific aspects of LEAD management.

Purpose of the Study:

  • To compare the risk, diagnosis, and treatment outcomes of LEAD in women versus men.
  • To highlight potential disparities in medical care and revascularization outcomes for female patients.
  • To emphasize the need for gender-sensitive approaches in managing peripheral artery disease.

Main Methods:

  • Review of epidemiological data on LEAD prevalence in men and women.
  • Analysis of diagnostic patterns and symptom presentation across genders.
  • Comparative study of morbidity rates following revascularization procedures in male and female cohorts.

Main Results:

  • Women exhibit a risk of LEAD comparable to men.
  • LEAD symptoms in women are frequently absent, atypical, or underestimated, resulting in diagnosis at later disease stages.
  • Women demonstrate a higher morbidity rate than men post-revascularization, irrespective of disease severity or procedure type.

Conclusions:

  • Gender-specific considerations are crucial for timely LEAD diagnosis and effective management.
  • Current medical care pathways may not be optimally adapted for women with LEAD.
  • Addressing gender disparities in LEAD care is essential to improve revascularization outcomes for women.

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