Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Relationship Formation02:12

Relationship Formation

46.3K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
46.3K
Ending Relationships01:28

Ending Relationships

205
The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
205
Pharmacokinetic–Pharmacodynamic Relationship: Duration of Dose-Effect Relationship01:14

Pharmacokinetic–Pharmacodynamic Relationship: Duration of Dose-Effect Relationship

23
For drugs producing a quantal response, onset occurs when plasma concentration reaches a minimum effective level (Cmin). The drug's action duration depends on how long the plasma concentration remains above Cmin.Two primary factors influence this duration: dose size and the rate of drug removal from the action site. Both depend on the drug's redistribution to poorly perfused tissues and elimination processes. A larger dose promotes rapid onset and prolongs the effect's duration.Consider a...
23
Relationship Growth01:27

Relationship Growth

231
Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...
231
Adrenergic Receptors: ɑ Subtype01:31

Adrenergic Receptors: ɑ Subtype

3.0K
Adrenoceptors are classified into α and ꞵ classes based on their potencies to catecholamine agonists. α-adrenoceptors show the following order of catecholamine potency:
Adrenaline ≥ Noradrenaline >> Isoprenaline
α-adrenoceptors are further divided into α1 and α2-adrenoceptors.
α1-Adrenoceptors: These receptors are located postsynaptically on the effector organs and cause constriction of smooth muscle mediated by activation of phospholipase...
3.0K
Adrenergic Receptors: β Subtype01:26

Adrenergic Receptors: β Subtype

3.9K
β-adrenoceptors have varied sensitivities towards adrenaline, noradrenaline, and isoprenaline. The order of agonist potency is as follows:
Isoprenaline > Adrenaline > Noradrenaline
Neurotransmitter binding to these receptors causes activation of adenylyl cyclase resulting in increased concentrations of cAMP and modulation of calcium ion channels within the cell. They are further classified into β1, β2, and β3 subtypes.
β1-adrenoceptors: β1-adrenoceptors...
3.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Review of the Use of Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Malignancy in Pediatric Patients.

Cancers·2023
Same author

<i>In Situ</i> Study of Structure Formation under Stress in Stretchable Conducting Nanocomposites.

The journal of physical chemistry letters·2023
Same author

SARS-CoV-2 vaccination induced cerebral venous sinus thrombosis: Do megakaryocytes, platelets and lipid mediators make up the orchestra?

Free neuropathology·2023
Same author

The Role of Montelukast Sodium in Children with Adenoid Hypertrophy - A Comparative Study.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2023
Same author

AIE-active cyclometalated iridium(III) complexes for the detection of lipopolysaccharides and wash-free imaging of bacteria.

Dalton transactions (Cambridge, England : 2003)·2023
Same author

Comparison of Radiological and Clinical Outcomes between Expandable and Non-expandable Cages Following Cervical Corpectomy: A Systematic Review and Meta-analysis.

Asian spine journal·2023

Related Experiment Video

Updated: Feb 15, 2026

Evaluating Cell Death Signaling by Immunofluorescence in a Rat Model of Ischemic Stroke
11:32

Evaluating Cell Death Signaling by Immunofluorescence in a Rat Model of Ischemic Stroke

Published on: January 3, 2025

1.6K

Relationship Between Visceral Infarction and Ischemic Stroke Subtype.

Caitlin Finn1, Peter Hung1, Praneil Patel1

  • 1From the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, NY (C.F., P.H., H.K.); and Departments of Radiology (P.P., A.G.) and Neurology (A.G., H.K.), Weill Cornell Medical College, New York, NY.

Stroke
|January 27, 2018
PubMed
Summary

Cryptogenic strokes, often presumed embolic, were linked to visceral infarcts. This study found a higher prevalence of kidney and spleen infarcts in cardioembolic and cryptogenic stroke patients compared to others.

Keywords:
atherosclerosisembolismsplenic infarctionstroketomography

More Related Videos

Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area
09:08

Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area

Published on: February 2, 2017

17.2K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.7K

Related Experiment Videos

Last Updated: Feb 15, 2026

Evaluating Cell Death Signaling by Immunofluorescence in a Rat Model of Ischemic Stroke
11:32

Evaluating Cell Death Signaling by Immunofluorescence in a Rat Model of Ischemic Stroke

Published on: January 3, 2025

1.6K
Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area
09:08

Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area

Published on: February 2, 2017

17.2K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.7K

Area of Science:

  • Neurology
  • Radiology
  • Vascular Medicine

Background:

  • Most cryptogenic strokes are presumed to have an embolic origin.
  • Visceral infarcts, such as renal or splenic, are typically embolic in nature.

Purpose of the Study:

  • To investigate the association between cryptogenic strokes and visceral infarcts.
  • To determine if cryptogenic strokes share embolic characteristics with visceral infarcts.

Main Methods:

  • Patients from the Cornell Acute Stroke Academic Registry (CAESAR) with abdominal CT scans were analyzed.
  • Stroke subtypes were classified, and the presence of renal or splenic infarcts was assessed.
  • Statistical analyses, including Fisher exact test and logistic regression, were employed.

Main Results:

  • Among 227 patients, 59 had visceral infarcts (35 renal, 27 splenic).
  • Visceral infarction prevalence was significantly higher in cardioembolic (34.2%) and cryptogenic (23.9%) strokes compared to noncardioembolic strokes (12.5%).
  • Logistic regression confirmed significant associations between visceral infarcts and both cardioembolic (OR 3.5) and cryptogenic strokes (OR 3.3).

Conclusions:

  • The prevalence of visceral infarction varies significantly across ischemic stroke subtypes.
  • Cardioembolic and cryptogenic strokes show a higher association with visceral infarcts, suggesting a potential shared embolic etiology.