Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Predator-Prey Interactions02:39

Predator-Prey Interactions

21.8K
Predators consume prey for energy. Predators that acquire prey and prey that avoid predation both increase their chances of survival and reproduction (i.e., fitness). Routine predator-prey interactions elicit mutual adaptations that improve predator offenses, such as claws, teeth, and speed, as well as prey defenses, including crypsis, aposematism, and mimicry. Thus, predator-prey interactions resemble an evolutionary arms race.
21.8K
Epithelial Tissues and Their Functions01:23

Epithelial Tissues and Their Functions

41.4K
Epithelial tissues are large sheets of cells covering all of the surfaces of the body. These surfaces can be internal or external, for example, skin, airways, the digestive tract, the urinary system, and the reproductive system. Hollow organs and body cavities that do not connect to the body's exterior, including blood vessels and serous membranes, are lined by epithelial tissue known as the endothelium.
Epithelial tissues provide the body's first line of protection from physical,...
41.4K
Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

22.9K
Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
22.9K
Van der Waals Interactions01:24

Van der Waals Interactions

72.2K
Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.
72.2K
piRNA - Piwi-interacting RNAs02:57

piRNA - Piwi-interacting RNAs

7.7K
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
7.7K
Classification of Epithelial Tissues: Stratified Epithelium01:29

Classification of Epithelial Tissues: Stratified Epithelium

13.3K
Stratified epithelium consists of several stacked layers of cells. They provide the durability to withstand constant physical and chemical attacks. Stratified epithelium is named after the shape of the most apical layer of cells. Stratified squamous epithelium is the most common type found in the human body. In this tissue, the apical cells are squamous, whereas the basal layer contains either columnar or cuboidal cells. The basal cells divide to form new daughter cells, which gradually become...
13.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Viral infection triggers interferon-induced expulsion of live Cryptococcus neoformans by macrophages.

PLoS pathogens·2020
Same author

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis.

PLoS pathogens·2018
Same author

Characterizing the Mechanisms of Nonopsonic Uptake of Cryptococci by Macrophages.

Journal of immunology (Baltimore, Md. : 1950)·2018
Same author

Quantifying donor-to-donor variation in macrophage responses to the human fungal pathogen Cryptococcus neoformans.

PloS one·2018
Same journal

Correction: Thaochan et al. Fungal-Infected Weeds: A Potential Source of Leaf Spot Disease in Rubber Trees from Southern Thailand. <i>J. Fungi</i> 2025, <i>11</i>, 220.

Journal of fungi (Basel, Switzerland)·2026
Same journal

Distinct Phenotype and Secondary Metabolite Profile Mark a Dominant <i>Aspergillus flavus</i> Outbreak Strain.

Journal of fungi (Basel, Switzerland)·2026
Same journal

Morphology, Chemistry, and Phylogeny Reveal Two New Species of the Genus <i>Lecidella</i> (Ascomycota, Lecanoraceae) from Anhui Province, China.

Journal of fungi (Basel, Switzerland)·2026
Same journal

Unlocking the Biocontrol Potential of Indigenous Soil Fungi: High-Performing Strains of <i>Beauveria bassiana</i> and <i>Metarhizium robertsii</i> Against the Tomato Leafminer <i>Tuta absoluta</i>.

Journal of fungi (Basel, Switzerland)·2026
Same journal

Unraveling CARD9 Mutations in Deep Dermatophytosis: A Genetic Gateway to Fungal Invasion and Immune Dysfunction.

Journal of fungi (Basel, Switzerland)·2026
Same journal

Draft Genome and Comparative Analysis of a <i>Cutaneotrichosporon jirovecii</i>-Related Yeast Recovered from a Human Fecal Sample.

Journal of fungi (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions
10:56

Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions

Published on: June 22, 2019

6.8K

Cryptococcus-Epithelial Interactions.

Leanne M Taylor-Smith1

  • 1Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, West Midlands, UK. l.m.taylorsmith@bham.ac.uk.

Journal of Fungi (Basel, Switzerland)
|January 27, 2018
PubMed
Summary
This summary is machine-generated.

Cryptococcus neoformans is a fungal pathogen that causes severe illness, primarily in immunocompromised individuals. This review focuses on how this fungus interacts with respiratory epithelial cells in the lungs.

Keywords:
Cryptococcusepithelial cellshost–fungal interactions

More Related Videos

Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
11:07

Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans

Published on: December 19, 2014

13.1K
Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans
08:24

Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans

Published on: February 27, 2018

14.5K

Related Experiment Videos

Last Updated: Feb 15, 2026

Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions
10:56

Complementary Use of Microscopic Techniques and Fluorescence Reading in Studying Cryptococcus-Amoeba Interactions

Published on: June 22, 2019

6.8K
Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
11:07

Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans

Published on: December 19, 2014

13.1K
Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans
08:24

Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans

Published on: February 27, 2018

14.5K

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Cryptococcus neoformans is a major cause of morbidity and mortality, particularly in individuals with compromised immune systems like those with HIV.
  • Infections begin with the inhalation of fungal cells, leading to initial contact with respiratory epithelial cells in the lungs.

Purpose of the Study:

  • To review the interactions between Cryptococcus neoformans and respiratory epithelial cells.
  • To explore the adhesion mechanisms, host immune responses, and fungal adaptations during this interaction.

Main Methods:

  • Literature review focusing on studies examining Cryptococcus neoformans and respiratory epithelium.
  • Analysis of research on fungal adhesion, cytokine/chemokine release, surfactant activity, and fungal metabolic/transcriptional responses.

Main Results:

  • Cryptococcus neoformans adheres to respiratory epithelial cells, though the capsule's role in adhesion is debated.
  • Respiratory epithelia mount an immune response through cytokine and chemokine release.
  • Surfactant components and fungal metabolic/transcriptional changes in response to epithelial encounter are key aspects.

Conclusions:

  • Understanding the early interactions between Cryptococcus neoformans and respiratory epithelia is crucial for developing targeted therapies.
  • Further research into adhesion dynamics, host-pathogen signaling, and fungal adaptation is warranted.