Epidemiology of Chronic Hepatitis C Infections at a Tertiary Care Centre in Oman

Said A Al-Busafi1, Halima Al-Shuaili2, Heba Omar3

  • 1Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.

Insights

This study describes chronic hepatitis C (CHC) in Oman, finding high rates of cirrhosis and liver cancer. Early screening and prevention policies are recommended to reduce the disease burden.

Area of Science:

  • Hepatology
  • Epidemiology
  • Public Health

Background:

  • Chronic hepatitis C (CHC) is a significant global cause of liver cirrhosis and hepatocellular carcinoma (HCC).
  • Limited epidemiological data exists for CHC in Oman, necessitating local characterization.
  • Understanding CHC epidemiology is crucial for targeted public health interventions.

Purpose of the Study:

  • To delineate the clinicopathological features of CHC patients in Oman.
  • To analyze the outcomes of CHC infection at a tertiary care hospital.
  • To provide baseline data for national hepatitis C control strategies.

Main Methods:

  • Retrospective, descriptive, hospital-based study.
  • Inclusion of 603 CHC patients at Sultan Qaboos University Hospital (2010-2015).
  • Analysis of demographic, clinical, laboratory, and radiological data.

Main Results:

  • The cohort comprised 65.8% males with a mean age of 44.8 years.
  • Key risk factors included intravenous drug abuse (23.9%) and blood transfusions (20.7%).
  • Hepatitis C virus genotypes 1 and 3 were most common; 33.0% had cirrhosis, and 23.1% had HCC at presentation.

Conclusions:

  • Significant prevalence of cirrhosis and HCC among CHC patients in Oman.
  • Low rates of liver transplantation for eligible patients.
  • Urgent need for national policies on CHC prevention and early screening.
Abstract

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