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Arteriosclerosis Is a Major Predictor of Small Bowel Vascular Lesions

Taiki Aoyama1, Akira Fukumoto2, Kenjiro Shigita2

  • 1Department of Gastroenterology, Hiroshima City Asa Citizens Hospital, 2-1-1 Kabe-minami, Asakita-ku, Hiroshima, 731-0293, Japan. t-aoyama@asa-hosp.city.hiroshima.jp.

Digestive Diseases and Sciences
|January 27, 2018
PubMed

Insights

Arteriosclerosis, particularly superior mesenteric artery calcification, independently predicts small bowel vascular lesions (SBVLs). This finding offers a new indicator for identifying patients at higher risk for SBVLs.

Area of Science:

  • Gastroenterology
  • Vascular Medicine
  • Radiology

Background:

  • Previous research focused on comorbidities associated with small bowel vascular lesions (SBVLs).
  • A need exists for a more fundamental predictor of SBVL presence.

Purpose of the Study:

  • To investigate atherosclerosis, both qualitatively and quantitatively, as a potential predictor of SBVLs.
  • To identify fundamental indicators for SBVL presence beyond patient comorbidities.

Main Methods:

  • Retrospective analysis of 79 patients with obscure gastrointestinal bleeding undergoing CT and endoscopy.
  • Assessment of arterial wall calcification using unenhanced CT and a modified Agatston scoring system for abdominal aorta calcium.
  • Evaluation of SBVL frequency, type, location, and correlation with clinical characteristics.

Main Results:

  • Small bowel vascular lesions (SBVLs) were identified in 34% of patients.
  • Arteriosclerosis (P = .0036) and superior mesenteric artery calcification (OR 16.3) were independent predictors of SBVLs.
  • The modified Agatston score was significantly higher in patients with SBVLs (6384 vs. 2666, P = .0023).

Conclusions:

  • Arteriosclerosis is associated with an increased likelihood of SBVLs.
  • Superior mesenteric artery calcification is a significant independent predictor of SBVLs.
  • Atherosclerosis assessment may aid in predicting SBVL presence in patients with obscure GI bleeding.
Abstract

Keywords:
ArteriosclerosisCalcificationSmall bowel vascular lesionsSuperior mesenteric artery

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