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Predictors of Pre-operative Anxiety in Indian Children
Ritu Malik1, Sandhya Yaddanpudi1, Nidhi Bidyut Panda1
1Department of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Insights
Pre-operative anxiety is common in Indian children undergoing surgery. Parental anxiety and socioeconomic status significantly predict a child's anxiety levels before surgery.
Area of Science:
- Pediatric Anesthesiology
- Child Psychology
- Socioeconomic Determinants of Health
Background:
- Pre-operative anxiety is a significant concern in pediatric surgical patients.
- Understanding predictors is crucial for developing targeted interventions.
Purpose of the Study:
- To identify predictors of pre-operative anxiety in school-going children in India.
- To analyze factors within individual, social, and healthcare domains.
Main Methods:
- Prospective observational study at a tertiary care hospital.
- Inclusion of children aged 7-12 years scheduled for elective surgery and their parents.
- Assessment of child and parental anxiety using STAI-C and STAI-P questionnaires, and child anxiety using the m-YPAS scale.
Main Results:
- High anxiety incidence increased from pre-operative assessment (48%) to anesthetic induction (95%).
- Parental anxiety (p=0.03) and socioeconomic background (p=0.03) were significant predictors of child's pre-operative anxiety.
- Poor mask induction quality was associated with more than 4 people present at induction (p=0.002).
Conclusions:
- Peri-operative anxiety is prevalent in Indian children.
- Parental anxiety and socioeconomic background are key predictors of pre-operative anxiety in this population.
Objective:
To identify the predictors of pre-operative anxiety in school-going children in India.
Methods:
A prospective observational study was done at a tertiary care teaching hospital. Children aged 7-12 y scheduled for elective surgery and their parents were enrolled. Pre-operative anxiety in children and parents was assessed using STAI-C and STAI-P questionnaires respectively. The child's anxiety in pre-op room, at the time of parental separation and induction of anesthesia were assessed using m-YPAS scale. Possible predictors of anxiety under 'individual', 'social' and 'healthcare' domains were analyzed using logistic regression. The quality of mask induction of anesthesia was assessed using Induction Compliance Checklist.
Results:
Sixty children completed the study successfully. Receiver operating characteristic (ROC) curve indicted mYPAS score ≥ 30 (observed score) to identify children with high anxiety as identified by STAI-C ≥37 (self-reported score). The incidence of high anxiety escalated from pre-operative time (48%) to the time of parental separation (72%) and increased further at anesthetic induction (95%). Parental anxiety (p = 0.03) and socioeconomic background (p = 0.03) were significant predictors of the child's pre-operative anxiety. The presence of >4 people at induction (p = 0.002), but not pre-operative anxiety, was found significantly more in children with poor quality of mask induction.
Conclusions:
The incidence of peri-operative anxiety in Indian children is significant. Parental anxiety and socioeconomic background were found significant predictors of high pre-operative anxiety in our set-up.
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pre-mRNA Processing
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
Pre-mRNA Processing: Modification of pre-mRNA Ends
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a cap to the 5' end of the growing transcript. In this process, a 5' phosphate is replaced by modified guanosine that has a methyl group attached (7-methyl guanosine). This 5' cap helps...

