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Area of Science:

  • Neuroscience
  • Endocrinology
  • Psychiatry

Background:

  • Hypoglycemia symptoms can be mistaken for the sedative effects of antipsychotic medications.
  • This diagnostic challenge is particularly relevant in patients with psychiatric disorders, who are often prescribed these drugs.
  • Overlooking hypoglycemia can lead to delayed or incorrect treatment, potentially worsening patient outcomes.

Purpose of the Study:

  • To report a case of hypoglycemia associated with hyperinsulinemia.
  • To identify the causative agent, quetiapine, a second-generation antipsychotic.
  • To emphasize the importance of considering drug-induced hypoglycemia in psychiatric patients.

Main Methods:

  • A case study approach was used.
  • Clinical presentation, laboratory findings, and medication history were reviewed.
  • The patient was diagnosed with bipolar disorder and presented with hypoglycemic symptoms.

Main Results:

  • The patient experienced hypoglycemia.
  • Laboratory tests revealed hyperinsulinemia.
  • Quetiapine was identified as the likely cause of the drug-induced hypoglycemia.

Conclusions:

  • Clinicians should maintain a high index of suspicion for hypoglycemia in patients with psychiatric disorders, especially when treated with second-generation antipsychotics.
  • Quetiapine can induce hypoglycemia through hyperinsulinemia.
  • Awareness of this potential adverse effect is crucial for accurate diagnosis and management.