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Patient blood management in cardiac surgery: Results
A Pajares1, L Larrea2, I Zarragoikoetexea1
1Área Anestesia Cardíaca, Servicio de Anestesiología y Reanimación, Hospital Universitari i Politècnic La Fe, Valencia, España.
Insights
Implementing a blood-saving programme in cardiac surgery reduced transfusion rates and pulmonary complications. While blood product use decreased, fibrinogen increased, and mortality remained unchanged.
Area of Science:
- Cardiovascular Surgery
- Transfusion Medicine
- Patient Blood Management
Background:
- Elective cardiac surgery often necessitates blood transfusions, carrying associated risks.
- Optimizing blood management strategies is crucial for improving patient outcomes and reducing healthcare costs.
Purpose of the Study:
- To assess the impact of a blood-saving program on transfusion rates and complications in patients undergoing elective cardiac surgery.
- To analyze the effectiveness of a comprehensive blood management protocol in a real-world clinical setting.
Main Methods:
- A retrospective, comparative study of 604 adult patients undergoing elective cardiac surgery.
- Patients were divided into two groups: pre-implementation (293) and post-implementation (311) of a blood-saving protocol.
- Data collected included transfusion rates, complication incidence, hospital stay, and mortality.
Main Results:
- The post-implementation group showed a significant reduction in overall blood product transfusion rates (89.5% vs. 67.6%).
- Specific reductions were observed in red blood cell concentrates, fresh frozen plasma, and platelet transfusions.
- Pulmonary complications decreased significantly (57.8% vs. 43.1%), while fibrinogen use increased (16.4% vs. 49%).
Conclusions:
- Implementation of a blood-saving program effectively reduces blood product transfusion in cardiac surgery.
- The program led to a decrease in pulmonary complications and intensive care unit length of stay.
- While beneficial, the program did not impact the overall mortality rate.
Objective:
The main objective of the study was to evaluate the effect of implementing a blood-saving programme in patients undergoing elective cardiac surgery with an analysis of the transfusion rate and complications.
Materials And Methods:
A single-centre, observational, retrospective, comparative study which included 604 consecutive patients older than 15 years old undergoing elective cardiac surgery. Two groups of patients were created according to whether or not they were included in a blood-saving protocol, and analysed between December 2012 and July 2013 (293 patients, prep group) and April 2015 to May 2016 (311 patients, posp group).
Results:
The overall blood product transfusion rate was reduced in the posp group (89.5 vs. 67.6%; P<0.001), as well as individually: red blood cell concentrates (83.6%; P<0.001), fresh frozen plasma (36.2 vs. 21.2%; P<0.001), platelets (40.8 vs. 32.7; P<0.001). By contrast, fibrinogen use increased from 16.4 to 49% (P<0.001). Postoperative complications were similar in both groups, except for pulmonary complications (57.8 vs. 43.1%; P<0.001). Length of hospital stay was similar in both groups except in the Critical Care Unit with longer stay for the prep group (5.81±8.00 vs. 4.18±4.38; P=0.002). Mortality did not change.
Conclusions:
The implementation of a blood-saving programme in the cardiac surgery area has favourable consequences, such as a saving in blood product and a reduction of pulmonary complications, although without decreasing the mortality rate.
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