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Related Experiment Videos

Chronic stress and major depression.

N Breslau, G C Davis

    Archives of General Psychiatry
    |April 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Chronic stress in mothers of children with disabilities did not increase rates of major depressive disorder (MDD). However, it was linked to earlier onset and more lifetime episodes of MDD.

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    Area of Science:

    • Psychiatry
    • Psychology
    • Epidemiology

    Background:

    • Mothers of children with disabilities often experience chronic stress.
    • The relationship between chronic stress and major depressive disorder (MDD) requires further investigation.

    Purpose of the Study:

    • To compare the rates and characteristics of DSM-III major depressive disorder (MDD) in mothers of children with disabilities versus a control group.
    • To examine the potential etiologic role of chronic stress in MDD.

    Main Methods:

    • A comparative study involving mothers of children with disabilities (n=310) and a general population control sample (n=357).
    • Diagnostic Interview Schedule from the National Institute of Mental Health used for DSM-III MDD ascertainment.

    Main Results:

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    • No significant difference in MDD rates between the chronic stress and control groups.
    • Mothers in the chronic stress group reported earlier age of onset and more lifetime episodes of MDD.
    • No differences in the symptomatology of the worst episode between the groups.

    Conclusions:

    • Chronic stress does not appear to be an etiologic factor for MDD.
    • Chronic stress is not associated with a unique symptom profile or more severe MDD episodes.
    • Chronic stress may play a role in precipitating MDD episodes, but further research is needed.