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[Importance of Virchow-Robin spaces]
1Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße, 66424, Homburg-Saar, Deutschland. wolfgang.reith@uks.eu.
Der Radiologe
|January 28, 2018
Summary
Virchow-Robin spaces are normal brain fluid cavities. Expanded spaces may link to diseases like Alzheimer's and hypertension, requiring differential diagnosis.
Area of Science:
- Neuroimaging
- Neuroanatomy
- Pathology
Background:
- Virchow-Robin spaces are physiological perivascular cavities in the brain.
- Typically 5 mm, they are hyperintense on T2-weighted MRI sequences.
- They are thought to aid interstitial fluid drainage via the cervical lymph system.
Purpose of the Study:
- To review the characteristics and clinical relevance of Virchow-Robin spaces.
- To discuss their association with neurological diseases and differential diagnoses.
- To highlight potential complications of enlarged spaces.
Main Methods:
- Review of neuroimaging characteristics (T2-weighted sequences).
- Discussion of typical locations (basal ganglia, mesencephalon, white matter).
- Analysis of associations with various neurological conditions.
Main Results:
- Virchow-Robin spaces are common, normal findings.
- Enlarged spaces are associated with Alzheimer's disease, cerebrovascular diseases, and hypertension.
- Differential diagnosis includes lacunar infarcts and tumors.
Conclusions:
- Virchow-Robin spaces are integral to brain physiology.
- Their expansion can indicate underlying pathology or lead to hydrocephalus.
- Accurate identification is crucial for neurological diagnosis.
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