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Updated: Feb 15, 2026

Basics of Multivariate Analysis in Neuroimaging Data
Published on: July 24, 2010
Multivariate normal maximum likelihood with both ordinal and continuous variables, and data missing at random
Joshua N Pritikin1, Timothy R Brick2, Michael C Neale3
1Department of Psychiatry and Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, 800 E. Leigh St., Richmond, VA, 23219, USA. jpritikin@pobox.com.
Abstract:
A novel method for the maximum likelihood estimation of structural equation models (SEM) with both ordinal and continuous indicators is introduced using a flexible multivariate probit model for the ordinal indicators. A full information approach ensures unbiased estimates for data missing at random. Exceeding the capability of prior methods, up to 13 ordinal variables can be included before integration time increases beyond 1 s per row. The method relies on the axiom of conditional probability to split apart the distribution of continuous and ordinal variables. Due to the symmetry of the axiom, two similar methods are available. A simulation study provides evidence that the two similar approaches offer equal accuracy. A further simulation is used to develop a heuristic to automatically select the most computationally efficient approach. Joint ordinal continuous SEM is implemented in OpenMx, free and open-source software.
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