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Updated: Feb 15, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
Acute lymphoblastic leukemia secondary to myeloproliferative neoplasms or after lenalidomide exposure
Ahmad Alhuraiji1, Kiran Naqvi1, Yang O Huh2
1Department of Leukemia University of Texas MD Anderson Cancer Center Houston 77030 Texas.
Abstract:
Philadelphia-negative (Ph-) myeloproliferative neoplasms (MPN) do rarely transform to acute lymphoblastic leukemia (ALL). While causality is difficult to establish, a few cases of ALL arising after exposure to lenalidomide for registered indications (multiple myeloma, myelodysplastic syndrome with 5q deletion) have been described in the literature.
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