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Anticoagulant Drugs: Low-Molecular-Weight Heparins

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...

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Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating

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Published on: June 23, 2018

Subcutaneous hematomas from prophylactic heparin use.

Abhilash Koratala¹, Deepti Bhattacharya¹

¹Division of Nephrology, Hypertension and Renal Transplantation University of Florida Gainesville Florida.

Clinical Case Reports

|January 30, 2018

Summary

Subcutaneous heparin, used to prevent deep vein thrombosis (DVT), can cause injection site complications like hematomas. These hematomas may occur without visible bruising, as observed in this case.

Keywords:

Hematoma heparin prophylaxis

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Area of Science:

Medicine
Pharmacology

Background:

Heparin is a common anticoagulant for preventing deep vein thrombosis (DVT) in hospitalized patients.
Subcutaneous administration of heparin is associated with potential injection site complications.

Purpose of the Study:

To highlight a specific complication of subcutaneous heparin administration.
To report a case of hematoma formation without visible bruising following heparin injection.

Main Methods:

Case report detailing the clinical presentation and management.
Review of relevant medical literature on heparin-induced complications.

Main Results:

The patient developed a hematoma at the heparin injection site.
The hematoma was present without any accompanying visible bruising or significant pain.

Conclusions:

Subcutaneous heparin can lead to hematoma formation, which may not always be accompanied by external bruising.
Clinical vigilance is necessary to detect such complications even in the absence of obvious signs.