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Updated: Feb 15, 2026
06:45
Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
898
Prophylactic negative pressure wound therapy after lower extremity fracture surgery: a pilot study
Siem A Dingemans1, Merel F N Birnie1, Manouk Backes1
1Department of Surgery, Academic Medical Center, Trauma Unit, Meibergdreef 9, PO Box 22660, 1100, Amsterdam, DD, Netherlands.
International Orthopaedics
|January 30, 2018
Summary
A pilot study evaluated a new portable negative pressure wound therapy (NPWT) device for lower extremity fractures. While 7.5% of patients experienced surgical site infections, the incidence was not significantly lower than historical controls.
Area of Science:
- Orthopedic Surgery
- Wound Management
- Infectious Disease Prevention
Background:
- Infectious complications after lower extremity fracture surgery pose significant challenges.
- These complications result in a substantial socio-economic burden.
- Effective preventative strategies are crucial for patient outcomes.
Purpose of the Study:
- To assess the feasibility of a novel portable, single-use negative pressure wound therapy (NPWT) device.
- To investigate the efficacy of this NPWT device in preventing surgical site infections (SSIs) after major foot and ankle surgery.
Main Methods:
- A prospective case series of patients undergoing major foot and ankle fracture surgery.
- Patients were case-matched with a historical cohort from the same institution.
- Surgical site infections were monitored for 30 days post-surgery using CDC criteria.
Main Results:
- Sixty patients were included in the study.
- Four surgical site infections (7.5%) occurred: two superficial (3.3%) and two deep (3.3%).
- The incidence of SSIs in the prospective cohort (4.3%) was not statistically significantly different from the historical cohort (14.9%).
Conclusions:
- Prophylactic use of this NPWT device resulted in a 7.5% surgical site infection rate.
- The study did not demonstrate a statistically significant reduction in SSIs compared to historical controls.
- Further research is needed to optimize NPWT use in this patient population.
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