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Pediatric Invasive Aspergillosis

Rachel L Wattier1, Lynn Ramirez-Avila2

  • 1Department of Pediatrics, Division of Infectious Diseases and Global Health, University of California-San Francisco, 550 16th St, 4th Floor, Box 0434, San Francisco, CA 94143, USA. rachel.wattier@ucsf.edu.

Journal of Fungi (Basel, Switzerland)
|January 30, 2018
PubMed

Insights

Invasive aspergillosis (IA) is a growing concern in children, requiring specific approaches. This review details key differences in pediatric IA epidemiology, symptoms, diagnosis, and treatment.

Area of Science:

  • Pediatric Infectious Diseases
  • Mycology
  • Immunocompromised Host Management

Background:

  • Invasive aspergillosis (IA) is increasingly prevalent in pediatric populations.
  • Improved survival rates in immunocompromised children contribute to rising IA cases.
  • Pediatric IA presents unique challenges compared to adult cases.

Purpose of the Study:

  • To review the specific epidemiology of pediatric IA.
  • To outline distinct clinical manifestations in children.
  • To highlight differences in diagnostic and therapeutic strategies for pediatric IA.

Main Methods:

  • Comprehensive literature review focusing on pediatric IA studies.
  • Analysis of epidemiological trends in immunocompromised children.
  • Synthesis of current diagnostic and treatment guidelines for pediatric IA.

Main Results:

  • Pediatric IA epidemiology shows distinct patterns influenced by underlying conditions.
  • Clinical presentation of IA in children can differ significantly from adults.
  • Diagnostic approaches and therapeutic options require age-specific considerations.

Conclusions:

  • Pediatric IA necessitates tailored management strategies.
  • Understanding age-specific differences is crucial for effective diagnosis and treatment.
  • Further research into pediatric IA is warranted to optimize patient outcomes.

Keywords:
antifungalaspergillosispediatric

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