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Updated: Aug 3, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
Published on: August 2, 2017
[REM-sleep behavior disorder and sleepwalking in a patient with Parkinson's disease and essential tremor]
M R Nodel1, S L Tsenteradze2, M G Poluektov2
1Sechenov First Moscow State Medical University, Moscow, Russia; Russian Reseach and Clinical Center of Gerontology, Moscow, Russia.
Abstract:
REM-sleep behavior disorder (RBD), a form of parasomnia, is characterized by motor and/or speech activity during sleep corresponding to the dream content. RBD is currently considered as a marker of onset of neurodegenerative diseases (sinucleinopathies) and as a most specific early symptom of Parkinson's disease (PD). The authors describe a clinical case of a patient with the combination of essential tremor, initial signs of PD and RBD. A polysomnographic study has confirmed clinical signs of RBD and determined the disturbances of sleep architecture: the increase in falling asleep, number of awakenings, wakefulness during sleep, the absence of deep slow-wave sleep. The particular features of the patient were essential tremor and sleep walking.
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