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Fixed eruption due to rifampicin.
Indian Journal of Leprosy
|July 1, 1985
Summary
Cutaneous side effects from Rifampicin are uncommon. This report details a rare case of urticarial fixed eruption caused by Rifampicin, a reaction not previously documented.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Rifampicin is a crucial antibiotic for treating tuberculosis.
- Cutaneous adverse drug reactions (cADRs) to Rifampicin are generally infrequent, occurring in less than 5% of patients.
Observation:
- This case study documents an unusual cutaneous reaction to Rifampicin.
- The patient presented with an urticarial fixed drug eruption.
Findings:
- Fixed drug eruption (FDE) is a specific type of cutaneous adverse drug reaction.
- An urticarial presentation of FDE due to Rifampicin has not been previously reported in medical literature.
Implications:
- This finding expands the spectrum of known cutaneous side effects associated with Rifampicin.
- Clinicians should consider fixed drug eruption in the differential diagnosis of dermatological reactions to Rifampicin, even with an urticarial morphology.