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The effects of an 8-week computerized cognitive training program in older adults: a study protocol for a randomized
Lisanne F Ten Brinke1, John R Best1, Rachel A Crockett1
1Aging, Mobility, and Cognitive Neuroscience Laboratory, Department of Physical Therapy, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, 2215 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
This study investigates if computerized cognitive training (CCT), with or without exercise, can improve cognitive function in older adults. The findings may offer new strategies for healthy cognitive aging.
Area of Science:
- Gerontology
- Cognitive Neuroscience
- Behavioral Science
Background:
- The global population is aging, increasing the need for strategies to promote healthy cognitive aging and mitigate cognitive decline.
- Currently, no pharmaceutical cures exist for cognitive impairment and dementia, driving interest in lifestyle interventions.
- Commercial computerized cognitive training (CCT) has grown, but its efficacy in older adults remains largely unproven; exercise is a known cognitive enhancer.
Purpose of the Study:
- To conduct a proof-of-concept randomized controlled trial (RCT) evaluating a commercial CCT program in community-dwelling older adults.
- To examine the effects of CCT alone versus CCT combined with brisk walking on cognitive function.
- To explore the neural mechanisms underlying cognitive changes and assess long-term benefits.
Main Methods:
- An 8-week RCT involving adults aged 65-85 years, randomized into three groups: CCT (FBT), brisk walk followed by CCT (Ex-FBT), or an active control (BAT).
- Participants attended three 1-hour sessions weekly.
- Cognitive function was assessed at baseline, post-intervention, and at a 1-year follow-up.
Main Results:
- Results are pending, but the study is designed to determine if CCT, with or without exercise, improves cognitive function in older adults.
- The study will also assess the neural correlates of cognitive changes and the durability of effects over one year.
Conclusions:
- If effective, CCT programs, particularly when combined with exercise, could represent a viable strategy for promoting healthy cognitive aging.
- Long-term follow-up data will be crucial for understanding the sustained benefits of these interventions.
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