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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

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Left ventricular short-axis systolic function changes in patients with hypertrophic cardiomyopathy detected by

Jun Huang1, Zi-Ning Yan2, Yi-Fei Rui2

  • 1Department of Echocardiography, the Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China. 305669112@qq.com.

BMC Cardiovascular Disorders
|January 31, 2018
PubMed

Insights

Hypertrophic cardiomyopathy (HCM) impairs short-axis systolic function, with reduced circumferential and radial strain in patients. Two-dimensional speckle tracking imaging effectively assesses these cardiac function changes in HCM.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Genetic Diseases

Background:

  • Hypertrophic cardiomyopathy (HCM) is a genetic disorder characterized by left ventricular hypertrophy (LVH), myocardial fibrosis, and fiber disarray.
  • Assessing left ventricle function, particularly short-axis systolic function, is crucial in managing HCM.

Purpose of the Study:

  • To evaluate short-axis systolic function in Hypertrophic cardiomyopathy (HCM) patients using 2-dimensional speckle tracking imaging (2D-STI).
  • To determine the feasibility of 2D-STI parameters in assessing cardiac function in HCM.

Main Methods:

  • Echocardiography was used to acquire parasternal short-axis images at basal, middle, and apical levels in 37 HCM patients and 41 healthy controls.
  • 2D-STI measured peak systolic circumferential strain (endocardial, middle, epicardial layers), peak systolic radial strain, and peak systolic rotational degrees at different short-axis levels.

Main Results:

  • HCM patients exhibited significantly lower peak systolic circumferential strain (septum, anterior walls) and all peak systolic radial strain values compared to controls.
  • Increased rotational degrees at basal and middle short-axis levels were observed in HCM patients.
  • Interventricular septal thickness correlated with peak systolic circumferential strain of the septum wall.

Conclusions:

  • Short-axis systolic function is demonstrably impaired in Hypertrophic cardiomyopathy (HCM) patients.
  • 2D-STI parameters, including peak circumferential systolic strain, peak systolic radial strain, and rotation degrees, are highly feasible for assessing short-axis function in HCM.
Abstract

Keywords:
CircumferentialHypertrophic cardiomyopathyRadialStrainTwo-dimensional speckle tracking imaging

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