Communication between the leaflets of asymmetric membranes revealed from coarse-grain molecular dynamics simulations
Jonathan Shearer1, Syma Khalid2
1University of Southampton, Southampton, SO17 1BJ, United Kingdom.
Abstract:
We use coarse-grain molecular simulations to investigate the structural and dynamics differences between an asymmetric and a symmetrical membrane, both containing beta barrel transmembrane proteins. We find in where the dynamics of the two leaflets differ greatly, the slowest leaflet dominates the structural effects and importance of protein-lipid interactions.
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