Related Experiment Video

Updated: Feb 15, 2026

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
10:56

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes

Published on: September 15, 2018

8.5K

Hypercholesterolaemia - practical information for non-specialists

Handrean Soran1,2, Safwaan Adam1,2, Jamal B Mohammad3

  • 1Cardiovascular Research Group, Faculty of Biology, Medicine & Health, University of Manchester, UK.

Archives of Medical Science : AMS
|January 31, 2018
PubMed

Insights

Hypercholesterolaemia, a common condition, is a key cardiovascular risk factor. This review covers updated risk assessment and treatment strategies, focusing on low-density lipoprotein cholesterol targets.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Public Health

Background:

  • Hypercholesterolaemia is a prevalent medical condition.
  • It represents a significant modifiable cardiovascular risk factor.
  • Recent advancements have improved risk stratification and treatment.

Purpose of the Study:

  • To provide a non-specialist background on hypercholesterolaemia.
  • To review current risk assessment tools.
  • To discuss treatment initiation, targets, and the role of LDL cholesterol.

Main Methods:

  • Literature review of recent advancements in hypercholesterolaemia management.
  • Analysis of risk stratification tools.
  • Discussion of treatment guidelines and lipid targets.

Main Results:

  • Multiple risk assessment tools are available with varying merits.
  • Treatment decisions involve timing, target lipid levels, and specific interventions.
  • Low-density lipoprotein cholesterol plays a critical role in management.

Conclusions:

  • Effective management of hypercholesterolaemia is crucial for cardiovascular health.
  • Personalized risk assessment and tailored treatment are essential.
  • Understanding LDL cholesterol's role guides therapeutic strategies.

Keywords:
cardiovascualr riskhypercholesterolaemialipid disorderslow density lipoprotein cholesterolpractical recommendations

More Related Videos

A Practical Guide to Phylogenetics for Nonexperts12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

36.2K
Practical Methodology of Cognitive Tasks Within a Navigational Assessment05:19

Practical Methodology of Cognitive Tasks Within a Navigational Assessment

Published on: June 1, 2015

14.1K

Related Concept Videos

Characteristics of Practical Op Amps01:16

Characteristics of Practical Op Amps

A difference amplifier, a crucial component in numerous electronic devices, ideally amplifies only the difference-mode signal, which is the difference between two input signals. However, in practical circuits, the output voltage depends on both the differential gain and the common-mode gain.
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
881
Theoretical Foundations of Nursing Practice01:30

Theoretical Foundations of Nursing Practice

Theories play an essential role in organizing patient care. Theories refer to a proposed or followed belief, policy, or procedure that is the basis for action. Nursing theories are knowledge-based concepts that guide nurses' actions, influence nursing education and practice, and allow nurses to care for their patients.
Theories provide a perspective to assess patients' conditions and organize data and methods. They also assist in analyzing and interpreting information. They represent a...
18.0K
Equivalent Circuits for Practical Transformers01:28

Equivalent Circuits for Practical Transformers

The practical equivalent circuits of single-phase two-winding transformers exhibit significant deviations from their idealized versions due to the inherent properties of winding resistance and finite core permeability. These properties result in real and reactive power losses, affecting the transformer's performance. Understanding these deviations is crucial for designing more efficient transformers.
In a practical transformer, each winding exhibits resistance and leakage reactance. The...
1.4K
Sustainable Development01:43

Sustainable Development

As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K
pH01:24

pH

The potential of hydrogen (pH) is a measure of the acidity or basicity of a water-based solution determined by the concentration of hydronium ions (H3O+). In one liter of pure water at neutral pH, there are 1×10−7 moles of hydronium ions. However, the extensive range of hydronium ion concentrations present in water-based solutions makes measuring pH in moles cumbersome. Therefore, a pH scale was developed to convert moles of hydronium ions into the negative logarithm of the hydronium...
146.4K
Atomic Mass01:52

Atomic Mass

Atoms — and the protons, neutrons, and electrons that compose them — are extremely small. For example, a carbon atom weighs less than 2 × 10−23 g. When describing the properties of tiny objects such as atoms, we use appropriately small units of measure, such as the atomic mass unit (amu). The amu was originally defined based on hydrogen, the lightest element, then later in terms of oxygen. Since 1961, it has been defined with regard to the most abundant isotope of carbon, atoms of which...
70.7K