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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Open Globe Injury: Demographic and Clinical Features
Sevinc Sahin Atik1, Seyda Ugurlu, Emine Deniz Egrilmez
1Department of Ophthalmology, Katip Celebi University, Ataturk Teaching and Research Hospital, Karabaglar, Izmir, Turkey.
Open globe injuries (OGIs) often cause visual impairment. This study analyzed OGI clinical features and outcomes, finding that while some patients improve, many experience poor visual acuity, highlighting the need for better prognostic indicators.
Area of Science:
- Ophthalmology
- Trauma Surgery
- Public Health
Background:
- Open globe injuries (OGIs) represent a significant global cause of vision loss.
- This study investigates the clinical characteristics and visual outcomes of OGIs at a major Turkish teaching hospital.
Purpose of the Study:
- To evaluate the clinical features of open globe injuries.
- To assess the visual outcomes following treatment for OGIs.
- To identify potential prognostic factors for visual recovery in OGI patients.
Main Methods:
- Retrospective analysis of 156 patients (159 eyes) with OGIs from January 2009 to December 2013.
- Collection of data on demographics, injury mechanisms, and visual acuity (VA) at presentation and final follow-up.
- Calculation of Ocular Trauma Scores (OTS) and statistical analysis to determine prognostic factors.
Main Results:
- The study included 156 patients (77.6% male, mean age 36.89 years).
- Domestic and work-related accidents were the most frequent causes of OGI.
- While 55.7% of eyes showed improved best corrected visual acuity (BCVA), 44.3% had final BCVA equal to or worse than initial VA.
- A significant proportion of eyes in lower OTS categories (1 and 2) had poor visual outcomes, whereas all eyes in higher OTS categories (3 and 4) achieved good visual outcomes.
Conclusions:
- Certain clinical features may predict final visual outcomes in OGI patients.
- The Ocular Trauma Score (OTS), despite not being fully validated, shows potential as a valuable prognostic indicator for open globe injuries.
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