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[Recurrent wheezing: prevalence and associated factors in infants from Buenos Aires City, Argentina]
Gabriela Aída Szulman1, Héctor Freilij2, Ilse Behrends3
1Hospital de Niños Ricardo Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina; Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
Insights
Recurrent wheezing affects over a quarter of infants in Buenos Aires. Key risk factors include frequent colds, early onset, and maternal smoking during pregnancy, some of which are preventable.
Area of Science:
- Pediatrics
- Epidemiology
- Respiratory Medicine
Background:
- Bronchial obstruction episodes in early childhood are a common pediatric concern.
- Recurrent wheezing in infants presents a significant public health challenge.
- Understanding prevalence and associated factors is crucial for early intervention.
Purpose of the Study:
- To determine the prevalence of recurrent wheezing in infants in Buenos Aires City.
- To identify risk factors associated with wheezing and recurrent wheezing in this population.
Main Methods:
- A cross-sectional study was conducted from 2011 to 2012.
- Validated questionnaires were administered to parents of 1063 infants aged 12-15 months.
- Statistical analyses included chi-squared tests, Fisher's test, and logistic regression.
Main Results:
- The prevalence of recurrent wheezing (≥3 episodes) was 26.3%.
- Associated risk factors included male gender, ≥6 colds in the first year, early cold onset (<4 months), pneumonia, and maternal smoking.
- For recurrent wheezing, risk factors included ≥6 colds, early onset wheezing, and nocturnal wheezing.
Conclusions:
- The prevalence of recurrent wheezing in Buenos Aires infants is notably high.
- Several identified risk factors, such as maternal smoking and frequency of colds, are potentially preventable.
- Further research and preventative strategies are warranted.
Background:
The episodes of bronchial obstruction at early age constitute a frequent problem in Pediatrics. The aim of this study was to evaluate the prevalence of recurrent wheezing in infants in Buenos Aires City, as well as to identify any associated factors.
Methods:
Cross-sectional study performed from 2011 to 2012 in the Children Hospital Ricardo Gutiérrez, Buenos Aires City, as part of the International Study of Wheezing in Infants. A validated questionnaire was applied to parents of infants aged between 12 and 15 months. The prevalence of wheezing, mostly the recurrent episodes (three or more), and their probable associated factors were evaluated. Data were statistically analyzed with χ2, Fisher's test, binary and logistics multiple regression analysis. The significance level was 0.05.
Results:
Over 1063 infants, 58.9% (confidence interval (CI) 95% 55.9-61.9) presented at least one episode of wheezing and 26.3% (CI95% 23.8-29.9) three or more episodes (recurrent wheezing). Risk factors associated to wheezing were male gender (p=0.001), six or more episodes of cold during the first year of life (p <0.0001), age at first cold <4 months (p <0.0001); pneumonia (p <0.0001) and smoking during pregnancy (tobacco) (p=0.01). For recurrent wheezing, risk factors we considered as six or more episodes of cold during the first year of life (p <0.0001), early (< 4 month of age) onset wheezing (p <0.0001) and nocturnal wheezing (p <0.0001).
Conclusions:
The prevalence of recurrent wheezing among infants in Buenos Aires Ciy was high (26.3%). Some identified associated factors can be preventable.
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