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Computerised decision to reduce inappropriate medication in the elderly: a systematic review with meta-analysis
Luís Monteiro1,2, Tiago Maricoto1,3, Isabel S Solha4
1Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal.
This systematic review examines if computer decision support systems can effectively reduce potentially inappropriate medication use in the elderly, aiming to improve health outcomes. The findings will inform deprescribing strategies for older adults.
Area of Science:
- Gerontology
- Clinical Pharmacy
- Health Informatics
Background:
- Aging populations in developed countries face increased medication use and age-related physiological changes impacting drug efficacy and safety.
- Potentially inappropriate medications (PIMs) in the elderly are a significant concern, necessitating effective deprescribing strategies.
- Computerised decision support systems (CDSS) have shown promise in optimizing medical interventions, such as reducing unnecessary tests.
Purpose of the Study:
- To systematically review the literature on the effectiveness of CDSS in reducing PIMs among elderly patients.
- To assess the impact of CDSS-assisted deprescribing on health outcomes in the older adult population.
- To identify opportunities and barriers related to CDSS implementation for medication optimization in geriatrics.
Main Methods:
- A systematic review of studies will be conducted using major databases (MEDLINE, CENTRAL, EMBASE, Web of Science) and grey literature.
- Two independent reviewers will screen, select, and extract data from eligible articles, assessing methodological quality and bias.
- The review will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Main Results:
- This section is to be filled upon completion of the systematic review.
- The review will synthesize evidence on the effectiveness of CDSS in deprescribing PIMs.
- Potential impacts on health outcomes and patient safety will be evaluated.
Conclusions:
- This systematic review will provide evidence regarding the utility of CDSS in optimizing medication regimens for the elderly.
- Findings will inform the development of clinical guidelines and technological solutions for safer medication management in older adults.
- The study aims to contribute to improving the quality of care and health outcomes for the growing elderly population.
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