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Updated: Feb 15, 2026
08:00
The Clinical Application of Tumor Treating Fields Therapy in Glioblastoma
Published on: April 16, 2019
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Platelet-inspired medicine for tumor therapy
Jie Yang1, Shujun Wang2, Ping Liu1
1Department of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China.
Oncotarget
|February 1, 2018
Summary
Platelets can be engineered as drug delivery systems to combat rising tumor cases. This review explores platelet-tumor cell interactions and their potential in anti-tumor drug delivery.
Area of Science:
- Biomedical Engineering
- Oncology
- Drug Delivery Systems
Background:
- Increasing global tumor incidence necessitates novel therapeutic strategies.
- Conventional tumor treatments face limitations, including severe side effects and limited efficacy.
- There is a critical need for advanced drug delivery systems for improved tumor management.
Purpose of the Study:
- To review the complex interactions between platelets and tumor cells.
- To highlight the potential of platelets as a drug delivery vehicle for anti-tumor therapies.
- To summarize recent advancements in platelet-based drug delivery systems for cancer treatment.
Main Methods:
- Comprehensive literature review on platelet-tumor cell interactions.
- Analysis of studies employing platelets as carriers for anti-tumor drugs.
- Synthesis of current research on platelet drug-loaded systems in preclinical and clinical settings.
Main Results:
- Platelets exhibit multifaceted interactions with various tumor cells.
- Platelet-mediated drug delivery demonstrates promising anti-tumor effects in experimental models.
- Engineered platelet systems show potential for targeted delivery of chemotherapeutics.
Conclusions:
- Platelets represent a viable and versatile platform for developing novel anti-tumor drug delivery systems.
- Further research into platelet biology and engineering can optimize their therapeutic application against tumors.
- Platelet-based strategies offer a promising avenue for overcoming limitations of traditional cancer therapies.
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