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Updated: Feb 15, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Freshly squeezed: anaphylaxis caused by drone larvae juice
1Department of Dermatology, Venereology, and Allergology, University Hospital Würzburg, Würzburg, Germany.
Summary:
Drone larvae are mostly considered a by-product of beekeeping, but have recently been advo-cated as a high-protein source of food. There are as yet no data concerning their allergenic potential. We report on a 29-year old bee keeper who experienced an anaphylactic reaction following the consumption of a freshly prepared beverage from raw drone larvae. Larvae-specific sensitization was confirmed by prick-to-prick and basophil activation testing. Bee stings and classical bee products including honey and royal jelly were tolerated. This is the hitherto first report on IgE-mediated allergy to drone larvae. We suggest that a certain awareness towards the allergenicity of bee larvae is required.
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