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Updated: Feb 15, 2026

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
Published on: August 1, 2025
[Use of Hemospray® in post-sclerotherapy bleeding]
Beatriz González Ortiz1, Dora María Tapia Monge1, Alicia Reyes Cerecedo1
1Departamento de Gastroenterología Pediátrica, Hospital de Pediatría, Centro Médico Nacional SXXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Hemospray® is a safe and effective endoscopic hemostasis device for non-variceal gastrointestinal bleeding. This case study supports its use in pediatric patients with massive bleeding after sclerotherapy.
Area of Science:
- Gastroenterology
- Endoscopic Hemostasis
- Medical Devices
Context:
- Hemospray® is a novel device for endoscopic hemostasis in non-variceal gastrointestinal bleeding.
- It functions by increasing clotting factor concentration and creating a mechanical barrier.
- Indications include difficult access, massive bleeding, and coagulopathy.
Purpose:
- To report the successful use of Hemospray® in a pediatric patient with massive gastrointestinal bleeding.
- To evaluate the safety and efficacy of Hemospray® in controlling bleeding post-sclerotherapy in a child with acute liver failure and portal hypertension.
- To support the consideration of Hemospray® for massive bleeding control in pediatric patients.
Summary:
- A 2-year-old female with acute liver failure and portal hypertension experienced massive gastrointestinal bleeding after sclerotherapy.
- Hemospray® was applied endoscopically to control the bleeding.
- The procedure was successful, achieving hemostasis without complications.
Impact:
- Hemospray® demonstrated safety and efficacy in managing massive gastrointestinal bleeding in a pediatric case.
- This case suggests Hemospray® as a viable alternative for bleeding control in challenging pediatric gastrointestinal scenarios.
- Further investigation into Hemospray® use in pediatric populations is warranted.
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