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Glucose Sensing Using Capacitive Biosensor Based on Polyvinylidene Fluoride Thin Film.

Ambran Hartono1, Edi Sanjaya2, Ramli Ramli3

  • 1Department of Physics, Faculty of Sciences and Technology, UIN Syarif Hidayatullah Jakarta, Tangerang Selatan, Banten 15412, Indonesia. ambran.hartono@uinjkt.ac.id.

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Summary

A new polyvinylidene fluoride (PVDF) film capacitive biosensor effectively detects glucose. This low-cost device shows promise for developing advanced glucose sensing technologies.

Keywords:
GOx enzymePVDF filmcapacitive biosensorglucose sensing

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Area of Science:

  • Materials Science
  • Biotechnology
  • Sensor Technology

Background:

  • Capacitive biosensors offer a label-free detection method.
  • Polyvinylidene fluoride (PVDF) is a versatile polymer with potential in biosensor applications.
  • Accurate glucose monitoring is crucial for diabetes management.

Purpose of the Study:

  • To develop and evaluate a novel polyvinylidene fluoride (PVDF) film-based capacitive biosensor for glucose detection.
  • To investigate the sensor's performance across a range of glucose and enzyme concentrations.
  • To assess the feasibility of using PVDF for low-cost biosensor fabrication.

Main Methods:

  • Fabrication of a capacitive biosensor using a PVDF film sandwiched between two electrodes.
  • Immobilization of glucose oxidase (GOx) enzyme onto the electrode surface.
  • Measurement of the biosensor's output voltage in response to varying glucose concentrations (0.013–5.85 M) and GOx concentrations (4882.8–2.5 million units/L).
  • Analysis of dielectric properties at the electrolyte-electrode interface.

Main Results:

  • The PVDF film-based capacitive biosensor demonstrated a measurable voltage output.
  • Sensor output showed a positive correlation with increasing glucose concentrations up to 5.85 M.
  • The device performance was evaluated across a wide range of enzyme concentrations.

Conclusions:

  • PVDF film-based capacitive biosensors are suitable for glucose sensing applications.
  • The developed biosensor offers a promising platform for the cost-effective fabrication of glucose monitoring devices.
  • This technology presents opportunities for advancing electrochemical biosensing.