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Updated: Feb 15, 2026

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Published on: August 25, 2022
Regulatory Role of MicroRNAs in Muscle Atrophy during Exercise Intervention
Shufang Zhang1,2, Ning Chen3
1Graduate School, Wuhan Sports University, Wuhan 430079, China. shufangzhang0308@163.com.
Abstract:
Skeletal muscle comprising approximately 40% of body weight is highly important for locomotion and metabolic homeostasis. The growth and regeneration of skeletal muscle are highly organized processes; thus, it is not surprising to reveal certain complexity during these regulatory processes. Recently, a large number of evidence indicate that microRNAs can result in obvious impacts on growth, regeneration and metabolism of skeletal muscle. In this review, recent research achievements of microRNAs in regulating myogenesis, atrophy and aging during exercise intervention are discussed, which will provide the guidance for developing potential applications of microRNAs in health promotion and rehabilitation of sports injuries.
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