Magnetic resonance-guided interstitial high-intensity focused ultrasound for brain tumor ablation
Jacquelyn MacDonell1,2, Niravkumar Patel3, Sebastian Rubino1,2
1Departments of 1 Neuroscience and Experimental Therapeutics and.
Abstract:
Currently, treatment of brain tumors is limited to resection, chemotherapy, and radiotherapy. Thermal ablation has been recently explored. High-intensity focused ultrasound (HIFU) is being explored as an alternative. Specifically, the authors propose delivering HIFU internally to the tumor with an MRI-guided robotic assistant (MRgRA). The advantage of the authors' interstitial device over external MRI-guided HIFU (MRgHIFU) is that it allows for conformal, precise ablation and concurrent tissue sampling. The authors describe their workflow for MRgRA HIFU delivery.
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