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Antenatal chemotherapy in a case of diffuse large B-cell lymphoma
Akhil Rajendra1, Anup J Devasia2, Nirmal Raj Francis1
1Department of Internal Medicine, Christian Medical College, Vellore, Tamilnadu, India.
Abstract:
A 28-year-old pregnant woman in the sixth month of gestation presented with complaints of altered bowel habit for a month, on examination found to have generalised lymphadenopathy, pedal oedema and locally infiltrating ano-rectal growth. Rectal growth biopsy was reported as high-grade B-cell lymphoma. After a discussion in a multidisciplinary panel consisting of haemato-oncologists, obstetricians and physicians, she was planned to receive antenatal chemotherapy. She delivered a live baby of 1.86 kg at 36 weeks of gestational age by normal vaginal delivery. After 6 cycles of chemotherapy she had complete regression of the disease.
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