Primary skeletal muscle lymphoma: A case report.

Area of Science:

• Oncology
• Pathology

Background:

• Primary lymphomas of bone or skeletal muscle are exceptionally rare.
• Lymphomatous involvement of muscle typically occurs via direct invasion, metastasis, or rarely, as a primary tumor.
• This case focuses on primary muscle lymphoma, a less common presentation.

Purpose of the Study:

• To present a rare case of primary muscle non-Hodgkin lymphoma.
• To describe the associated clinicopathological findings.
• To review the relevant literature on primary muscle lymphomas.

Main Methods:

• A case study of a 41-year-old female patient with a painful mass in the right lower extremity.
• Surgical resection of the mass.
• Histopathological examination for diagnosis.
• Review of existing medical literature.

Main Results:

• Diagnosis of diffuse large B-cell lymphoma originating from the muscle with cutaneous and subcutaneous infiltration.
• Patient received six cycles of cyclophosphamide, hydroxydaunomycin, oncovin, and prednisone (CHOP) chemotherapy.
• Complete radiological response achieved post-treatment.

Conclusions:

• Primary muscle lymphoma is a rare entity requiring accurate diagnosis and tailored treatment.
• The CHOP regimen demonstrated efficacy in treating this case of primary muscle diffuse large B-cell lymphoma.
• Further research into primary muscle lymphomas is warranted.