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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Psoriasis in children.

Roxanne Pinson1, Bahman Sotoodian2, Loretta Fiorillo2,3

  • 1School of Medicine.

Psoriasis (Auckland, N.Z.)
|February 2, 2018
PubMed
Summary
This summary is machine-generated.

Pediatric psoriasis presents differently across age groups and impacts quality of life. Current treatments are varied, but new biologics need further study for safe and effective use in children.

Keywords:
biologicsepidemiologyjuvenile arthritispediatricphototherapysystemic treatmenttopical treatment

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Area of Science:

  • Dermatology
  • Pediatrics
  • Immunology

Background:

  • Pediatric psoriasis, a chronic inflammatory skin condition, presents unique challenges in diagnosis and management.
  • The disease's manifestation and impact evolve throughout infancy, childhood, and adolescence.
  • Psoriasis in children is associated with comorbidities like juvenile idiopathic arthritis and obesity, affecting their quality of life.

Purpose of the Study:

  • To provide a comprehensive overview of pediatric psoriasis management.
  • To review current and emerging treatment modalities for recalcitrant pediatric psoriasis.
  • To highlight knowledge gaps and future research directions in pediatric psoriasis treatment.

Main Methods:

  • Extensive literature review focusing on pediatric psoriasis.
  • Analysis of clinical presentations across different pediatric age groups.
  • Summary of topical, systemic, and biologic treatment options.

Main Results:

  • Psoriasis presentation varies significantly between infants, children, and adolescents.
  • Established treatments exist, but newer biologics approved for adults lack pediatric-specific investigation.
  • Comorbidities and quality of life are significant considerations in pediatric psoriasis management.

Conclusions:

  • Pediatric psoriasis requires tailored management strategies considering age-specific presentations and comorbidities.
  • Further clinical studies are essential to establish the safety and efficacy of novel biologic therapies in pediatric populations.
  • Development of treatment algorithms for pediatric psoriasis is needed to guide clinical practice.