Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocrine Signaling01:45

Endocrine Signaling

68.3K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
68.3K
What is the Endocrine System?00:46

What is the Endocrine System?

421.9K
The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
421.9K
The Endocrine System01:29

The Endocrine System

1.4K
The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
1.4K
An Overview of the Endocrine System01:10

An Overview of the Endocrine System

14.4K
The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
14.4K
Structures of the Endocrine System00:59

Structures of the Endocrine System

12.3K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
12.3K
Chemical Signaling in the Endocrine System01:08

Chemical Signaling in the Endocrine System

7.4K
A signaling cascade is a series of events that facilitates the transmission of information within or between cells, culminating in a targeted response in the recipient cell. As chemical messengers, hormones are pivotal in initiating and modulating these intricate signaling cascades based on their solubility.
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...
7.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Glucocorticoid-prescribing trends in congenital adrenal hyperplasia, 2017 to 2023.

Endocrine connections·2026
Same author

Enhancing transition care for adolescents and young adults with adrenal insufficiency in the Netherlands: a holistic model for improved patient outcomes.

Endocrine connections·2025
Same author

Standards of care for medical management of acromegaly in pituitary tumor centers of excellence (PTCOE).

Pituitary·2024
Same author

Venous thromboembolism in Cushing syndrome: results from an EuRRECa and Endo-ERN survey.

Endocrine connections·2024
Same author

Electronic reporting of rare endocrine conditions within a clinical network: results from the EuRRECa project.

Endocrine connections·2023
Same author

Pilot study to define criteria for Pituitary Tumors Centers of Excellence (PTCOE): results of an audit of leading international centers.

Pituitary·2023
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Methods to Test Endocrine Disruption in Drosophila melanogaster
09:43

Methods to Test Endocrine Disruption in Drosophila melanogaster

Published on: July 3, 2019

10.4K

[Endocrine paraneoplastic syndromes].

N Reisch1, M Reincke2

  • 1Medizinische Klinik IV, Klinikum der Universität München, Ziemssenstr. 1, 80336, München, Deutschland. nicole.reisch@med.uni-muenchen.de.

Der Internist
|February 2, 2018
PubMed
Summary
This summary is machine-generated.

Endocrine paraneoplastic syndromes involve ectopic hormone secretion by tumors, mimicking endocrine disorders. Treatment focuses on the primary tumor, with limited evidence for specific therapies.

Keywords:
AcromegalyCushing syndromeHormones, ectopicInappropriate ADH syndromePositron emission tomography computed tomography

More Related Videos

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays
08:00

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays

Published on: December 4, 2016

8.0K
Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome
08:31

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

Published on: July 31, 2016

14.6K

Related Experiment Videos

Last Updated: Feb 15, 2026

Methods to Test Endocrine Disruption in Drosophila melanogaster
09:43

Methods to Test Endocrine Disruption in Drosophila melanogaster

Published on: July 3, 2019

10.4K
Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays
08:00

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays

Published on: December 4, 2016

8.0K
Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome
08:31

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

Published on: July 31, 2016

14.6K

Area of Science:

  • Endocrinology
  • Oncology
  • Pathology

Background:

  • Endocrine paraneoplastic syndromes arise from ectopic bioactive substance production by neoplastic cells.
  • These syndromes, often from lung or GI tract tumors, mimic eutopic endocrine tumors, posing diagnostic challenges.

Purpose of the Study:

  • To review the characteristics and management of endocrine paraneoplastic syndromes.
  • To highlight the diagnostic difficulties and therapeutic strategies for these rare conditions.

Main Methods:

  • Literature review of endocrine paraneoplastic syndromes.
  • Analysis of common hormonal disturbances and their clinical presentations.

Main Results:

  • Common syndromes include those related to antidiuretic hormone (ADH), adrenocorticotropic hormone (ACTH), and growth hormone-releasing hormone (GHRH).
  • Syndromes can occur in highly malignant tumors, but do not always correlate with tumor stage or prognosis.
  • Evidence-based therapeutic recommendations are scarce.

Conclusions:

  • Treatment primarily involves addressing the underlying malignancy.
  • Symptomatic management is crucial in palliative settings.
  • Further research is needed to establish evidence-based guidelines.