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Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
Published on: April 11, 2017
Surfactant selection for a liquid foam-bed photobioreactor.
Agnes Janoska1, María Vázquez2, Marcel Janssen1
1AlgaePARC, Bioprocess Engineering, Wageningen University and Research, Wageningen, 6700AA, The Netherlands.
Pluronic F68 and Pluronic P84 surfactants are ideal for microalgae production in novel foam-bed photobioreactors. These surfactants exhibit good foaming properties and low toxicity, making them superior choices for this innovative technology.
Area of Science:
- Biotechnology
- Chemical Engineering
- Algal Biotechnology
Background:
- Microalgae cultivation is crucial for sustainable production.
- Liquid foam-bed photobioreactors offer innovative potential for microalgae production.
- Selecting appropriate foam stabilizing agents (surfactants) is critical for efficient reactor operation.
Purpose of the Study:
- To identify optimal surfactants for liquid foam-bed photobioreactors.
- To evaluate surfactants based on foaming properties, biodegradability, microalgae transport, and toxicity.
- To compare nonionic, cationic, and anionic surfactants with Chlorella and Scenedesmus microalgae.
Main Methods:
- Screening of ten surfactants based on four key criteria.
- Assessing foaming properties: foam stability, liquid holdup, and bubble size.
- Evaluating biodegradability, microalgae concentration in foam, and toxicity at specific concentrations.
Main Results:
- Poloxameric surfactants (Pluronic F68, P84) showed acceptable foaming properties.
- Natural surfactants (BSA, Saponin) and Tween 20 were rapidly biodegradable.
- Cationic surfactant CTAB uniquely increased microalgae concentration in foam; Pluronics were non-toxic at high concentrations.
Conclusions:
- Pluronics (F68 and P84) are the most suitable surfactants for liquid foam-bed photobioreactors.
- Pluronic F68 demonstrated slightly superior performance and is recommended for practical application.
- This research provides valuable insights for optimizing microalgae cultivation technologies.
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