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Management of venous thrombosis in the pediatric patient

Vlad C Radulescu1

  • 1Department of Pediatrics, University of Kentucky, Lexington, KY, USA.

Pediatric Health, Medicine and Therapeutics
|February 2, 2018
PubMed

Insights

Pediatric venous thromboembolism (VTE) is rising. This review covers evaluating and managing VTE in children, considering their unique hemostatic systems and current/emerging treatments.

Area of Science:

  • Pediatric Hematology
  • Vascular Medicine
  • Thrombosis Research

Background:

  • The incidence of pediatric venous thromboembolism (VTE) has notably increased in the last decade.
  • Managing childhood VTE requires adapting adult protocols due to distinct neonatal and pediatric hemostatic systems.
  • Understanding these differences is crucial for effective VTE care in younger populations.

Purpose of the Study:

  • To review the current diagnostic approaches for identifying thrombosis in pediatric patients.
  • To discuss established and novel therapeutic strategies for treating VTE in children.
  • To highlight the specific considerations for VTE management in newborns and children.

Main Methods:

  • Literature review of pediatric thrombosis studies.
  • Analysis of hemostatic system differences between adults and children.
  • Synthesis of current clinical guidelines and emerging research on VTE treatment.

Main Results:

  • Pediatric VTE evaluation necessitates tailored diagnostic pathways.
  • Treatment strategies must account for age-specific physiological differences.
  • Established anticoagulation methods are effective, with new interventions showing promise.

Conclusions:

  • Effective management of pediatric VTE requires a specialized approach.
  • Further research into age-specific treatments is warranted.
  • Early and accurate diagnosis combined with appropriate therapy improves outcomes for children with VTE.

Keywords:
anticoagulant therapychildrenthrombolytic therapyvenous thromboembolism

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