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Published on: November 21, 2017
Preoperative management of children with esophageal atresia: current perspectives
Filippo Parolini1, Anna Lavinia Bulotta1, Sonia Battaglia1
1Department of Pediatric Surgery, "Spedali Civili" Children's Hospital.
Insights
Esophageal atresia management has improved, but research gaps exist regarding prenatal diagnosis impact. This review focuses on current knowledge of prenatal and preoperative care for newborns with this congenital anomaly.
Area of Science:
- Neonatology
- Pediatric Surgery
- Congenital Anomalies
Background:
- Esophageal atresia is a complex congenital anomaly with improving outcomes due to advances in care.
- Current research emphasizes long-term morbidity, particularly respiratory and gastroesophageal issues.
- Despite improved survival, optimal prenatal and preoperative management strategies remain debated.
Purpose of the Study:
- To review current literature on the management of newborns with esophageal atresia.
- To focus on the critical aspects of prenatal management and preoperative assessment.
- To identify knowledge gaps concerning the impact of prenatal diagnosis.
Main Methods:
- Literature review of studies on esophageal atresia management.
- Analysis of research on prenatal diagnosis, neonatal critical care, and surgical procedures.
- Examination of data on medium- and long-term morbidity.
Main Results:
- Advances in prenatal diagnosis, neonatal care, and surgery have improved outcomes, even for premature infants.
- Focus is shifting towards understanding and managing long-term sequelae.
- Limited studies address the specific impact of prenatal diagnosis on patient outcomes.
Conclusions:
- Regular, multidisciplinary follow-up is essential for patients throughout adulthood due to frequent late sequelae.
- Further research is needed to clarify the role and impact of prenatal diagnosis in esophageal atresia management.
- Optimizing prenatal and preoperative strategies is crucial for complex cases.
Abstract:
Esophageal atresia remains one of the most challenging congenital anomalies of the newborn. In recent years, because of the advances in prenatal diagnosis, neonatal critical care, and surgical procedures, overall outcomes have improved substantially, including for premature children. Nowadays, most of the research is focused on medium- and long-term morbidity, with particular reference to respiratory and gastroesophageal problems; the high frequency of late sequelae in esophageal atresia warrants regular and multidisciplinary checkups throughout adulthood. Surprisingly, there are few studies on the impact of prenatal diagnosis and there is continuing debate over the prenatal and preoperative management of these complex patients. In this review, we analyze the literature surrounding current knowledge on the management of newborns affected by esophageal atresia, focusing on prenatal management and preoperative assessment.
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