Stress-induced response of mouse liver tyrosine aminotransferase after irradiation

On X-ray irradiated mice with a total dose of 800 R, the reactivity upon an aggressive agent (chloroform stress) administered at various delays after irradiation was studied. The reactivity of the animals has been emphasized by the hepatic induction of the tyrosine aminotransferase and by the adrenal ascorbic acid depletion. From the 3rd day after irradiation both these parameters showed a marked and irreversible decrease.