Related Experiment Video
Updated: Feb 15, 2026
12:08
The Use of Traditional Fear Tests to Evaluate Different Emotional Circuits in Cattle
Published on: April 22, 2020
9.2K
Development and validation of a small SNP panel for feed efficiency in beef cattle
M K Abo-Ismail1,2, N Lansink1, E Akanno1
1Livestock Gentec at University of Alberta, Edmonton, AB, Canada.
Journal of Animal Science
|February 2, 2018
Summary
Researchers developed a cost-effective SNP panel to improve feed efficiency in beef cattle. This panel identified key genes influencing traits like average daily gain and residual feed intake, aiding genetic selection.
Area of Science:
- Animal Genetics
- Quantitative Genetics
- Genomic Selection
Background:
- Feed efficiency is crucial for sustainable beef production.
- Genetic improvement of feed efficiency requires accurate genomic tools.
- Existing genotyping panels may not be cost-effective for all breeding programs.
Purpose of the Study:
- To develop and validate a cost-effective single nucleotide polymorphism (SNP) panel for genetic improvement of feed efficiency in beef cattle.
- To identify SNPs and genes associated with feed efficiency traits.
- To estimate genomic heritability using the developed SNP panel.
Main Methods:
- Screening of SNPs for functional impact and allele frequency in Angus and Hereford cattle.
- Association analyses using allele substitution and genotypic models on Angus, Hereford, and crossbred cattle.
- Estimation of genomic heritabilities using the developed SNP panel, significant SNPs, and a commercial 50K panel.
Main Results:
- Identified 63 SNPs within 43 genes associated with feed efficiency traits (P ≤ 0.05).
- Found significant effects of SNPs in GHR, CAST, MKI67, and CNTFR genes on residual feed intake (RFI), RFI adjusted for backfat (RFIf), and average daily gain (ADG).
- Gene enrichment analysis highlighted gland development and ion/cation transport as key physiological mechanisms, involving the Jak-STAT signaling pathway.
Conclusions:
- The developed 63-SNP panel is cost-effective and can be used for genetic improvement of feed efficiency in beef cattle.
- Identified SNPs and genes provide valuable targets for molecular breeding values.
- The study demonstrates the potential of targeted SNP panels for enhancing genetic gain in livestock populations.
Related Concept Videos
01:18Wood Panel Products
418
Wood panel products are essential materials used in construction for applications such as flooring, siding, and roofing, typically available in standard dimensions of 4 feet by 8 feet, with thicknesses varying from one-quarter of an inch to one and one-eighth inches. Among the most common types of wood panels is plywood, which is produced by gluing multiple layers of thin wood veneers under pressure. The grain of the outer veneers runs lengthwise, while the grains of the interior layers run...
418
01:29Reliability and Validity
14.1K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
14.1K
01:10In Vitro Drug Release Testing: Overview, Development and Validation
374
In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...
374
01:15Data Validation
2.4K
Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
Key parameters for method validation include:
Key parameters for method validation include:
2.4K
01:03Data Validation
7.0K
Data validation is an essential part of a comprehensive assessment. Validation is confirming or verifying and opening the door to gathering more assessment data as it clarifies vague or unclear data. The process of checking and verifying the collected information is called data validation. The primary purpose of data validation is to ensure data is as free from error, bias, and misinterpretation as possible.
Nursing assessment guides are generally based on holistic models rather than medical...
Nursing assessment guides are generally based on holistic models rather than medical...
7.0K
01:43Sustainable Development
15.2K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K