Progress in brain barriers and brain fluid research in 2017

Area of Science:

• Neuroscience
• Physiology
• Biomedical Science

Background:

• The Central Nervous System (CNS) relies on intricate fluid dynamics and barrier systems for optimal function.
• Understanding these elements is crucial for diagnosing and treating neurological disorders.

Discussion:

• This article reviews pivotal research from 2017 concerning CNS fluid dynamics.
• It also covers significant findings related to the integrity and function of CNS barriers.
• The selected papers represent major progress in the field.

Key Insights:

• Key advancements in cerebrospinal fluid (CSF) circulation and regulation are discussed.
• New insights into the blood-brain barrier (BBB) and its role in neuroprotection are presented.
• The importance of glial cells in maintaining CNS homeostasis is emphasized.

Outlook:

• Future research will likely focus on therapeutic interventions targeting CNS barriers.
• Further exploration of CSF dynamics may reveal novel diagnostic markers.
• Continued investigation into neuroinflammation and its impact on CNS barriers is expected.