Related Experiment Video
Updated: Feb 15, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Ultrasound Accuracy in Diagnosing Appendicitis in Obese Pediatric Patients
Bryan E Love1, Monica Camelo, Sarvenaz Nouri
1Riverside University Health System, University of California, Riverside, California, USA.
Insights
Ultrasound is a reliable diagnostic tool for appendicitis in obese and overweight children, showing a 100% positive predictive value. This study confirms its utility in the growing pediatric population with obesity.
Area of Science:
- Pediatric Radiology
- Diagnostic Imaging
- Abdominal Imaging
Background:
- Ultrasound (US) is increasingly used for diagnosing appendicitis in children.
- Its effectiveness in the growing population of obese pediatric patients requires further investigation.
Purpose of the Study:
- To evaluate the diagnostic utility of ultrasound for appendicitis in pediatric patients stratified by body mass index (BMI) percentile.
Main Methods:
- Retrospective review of pediatric patients (≤18 years) diagnosed with appendicitis from 2014-2016.
- Patients were categorized by BMI percentile.
- Ultrasound findings were compared with computed tomography (CT) results and clinical outcomes.
Main Results:
- Of 231 patients, 99 underwent ultrasound; 54 were positive for appendicitis, and 43 were nondiagnostic.
- Ultrasound demonstrated a 100% positive predictive value in overweight and obese children.
- Nondiagnostic ultrasounds were followed by CT, with no significant BMI difference between CT-only and ultrasound groups.
Conclusions:
- Ultrasound is a reliable imaging modality for diagnosing acute appendicitis in overweight and obese pediatric patients.
- The findings support the continued use and improvement of ultrasound techniques in this demographic.
Abstract:
The use of ultrasound to diagnose appendicitis in pediatric patients has been growing with the improvement of ultrasound technology and operator skills, but its utility in the increasingly obese pediatric population has not been thoroughly investigated. A retrospective review of all pediatric (≤18 years old) patients with appendicitis who were admitted at a single hospital from 2014 to 2016 was conducted. Patients were stratified into body mass index (BMI) percentile categories based on the centers for disease control guidelines. Comparisons were then made. There were 231 patients with an average BMI percentile of 72.6; 99 (42.9%) who had an ultrasound, of which 54 (54.5%) were positive for acute appendicitis, whereas 43 (43.4%) were nondiagnostic. In patients who had a nondiagnostic ultrasound, 37 had a CT demonstrating acute appendicitis. These were compared with 123 patients who had CT alone demonstrating acute appendicitis. The CT-only group was older (12 vs 9, P < 0.005), tended to be male (78 (63%) vs 15 (41%), P = 0.019), had fewer operations performed (81 (66%) vs 30 (81%), P = 0.048) but had no significant difference in BMI percentile (75.8 vs 71.7, P = 0.465). Ultrasound had a 100 per cent positive predictive value in obese and overweight children. Ultrasound is a reliable study in obese and overweight pediatric patients with acute appendicitis.
Related Concept Videos
Drug Dosing: Obese Patients
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

