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Updated: Feb 15, 2026

In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments
Published on: October 25, 2016
Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome
Benjamin S Robey1, Anne F Peery2, Evan S Dellon1,2
1Center for Esophageal Disease and Swallowing, University of North Carolina School of Medicine, Chapel Hill, NC.
Abstract:
Marfan syndrome is an autosomal dominant disorder involving mutation in the FBN1 gene, which encodes fibrillin-1, a protein critical to maintain the integrity of connective tissue. A mutation in this gene can affect multiple organ systems, but it is not classically associated with gastrointestinal complications. We describe a man with Marfan syndrome with multiple small bowel diverticula leading to small intestinal bacterial overgrowth and recurrent small bowel perforations.
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