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Updated: Feb 15, 2026

Kupffer Cell Isolation for Nanoparticle Toxicity Testing
Published on: August 18, 2015
Neglected nano-effects of nanoparticles in the interpretation of their toxicity
M Mionić Ebersold1, D Bonvin, H Hofmann
1Powder Technology Laboratory, Institute of Materials, Ecole Polytechnique Fédérale de Lausanne, Switzerland. marijanamionic@gmail.com.
Abstract:
Nanoparticles with smaller diameters have larger surface areas. Unfortunately, this fact is often neglected in their biomedical characterization, e.g. in the evaluation of their toxicity with cell viability tests. We here point out the different scientific conclusions drawn in such tests when considering the traditional mass or concentration of nanoparticles, or their surface areas.
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